using mounjaro for weight loss

How does Mounjaro work?

Mounjaro is a dual-acting medication that targets both the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. By activating these receptors, it enhances insulin secretion, reduces glucagon levels, slows gastric emptying, and promotes a feeling of fullness, thereby aiding in blood sugar control and weight management.

Mounjaro is approved for managing type 2 diabetes in adults to improve blood sugar control. Additionally, it has been authorized for weight management in individuals with obesity or overweight conditions accompanied by weight-related health issues.

Mounjaro is administered as a once-weekly subcutaneous injection using a pre-filled pen. The injection can be given in the stomach, thigh, or the back of the upper arm. It’s important to follow the administration instructions provided with the medication or by your healthcare provider.

Common side effects include nausea, vomiting, diarrhea, decreased appetite, constipation, and abdominal discomfort. These gastrointestinal issues often occur during dose escalation and may decrease over time.

If you miss a dose of Mounjaro, take the missed dose as soon as possible within 4 days (96 hours) after the missed dose. If more than 4 days have passed, skip the missed dose and take your next dose on the regularly scheduled day. Do not take two doses of Mounjaro within 3 days of each other.

Mounjaro should be stored in the refrigerator at temperatures between 36°F to 46°F (2°C to 8°C). If necessary, it can be stored unrefrigerated for up to 21 days, provided the temperature does not exceed 86°F (30°C). Keep the pens in their original packaging to protect them from light. Do not freeze Mounjaro pens. ​

The combination of Mounjaro with other weight loss medications has not been extensively studied. It’s essential to consult with your healthcare provider before combining treatments to ensure safety and efficacy.

While Mounjaro is primarily approved for type 2 diabetes management, it has also been authorized for weight management in individuals with obesity or overweight conditions accompanied by weight-related health issues.

Some individuals may notice effects, such as feeling fuller after eating, within as little as 12 hours. However, the timeframe can vary, and it may take several weeks to observe significant changes in blood sugar levels or weight.

While there isn’t a specific diet plan required, it’s advisable to follow a healthy and balanced diet, including plenty of vegetables, fruits, lean proteins, and whole grains. Avoid processed foods, fried foods, and items high in sugar. Staying hydrated and engaging in regular exercise can also enhance the medication’s effectiveness.

​Mounjaro, is known generically as tirzepatide.

It is a prescription only medication (POM) and is primarily approved for managing type 2 diabetes in adults to improve blood sugar control when combined with diet and exercise. Additionally, Mounjaro has shown significant efficacy in promoting weight loss, leading to its approval for weight management in individuals with obesity or overweight conditions accompanied by weight-related health issues.​

Risks and Considerations

Common side effects include:

  • nausea
  • vomiting
  • diarrhea
  • decreased appetite
  • constipation
  • abdominal discomfort

Serious but less common risks involve pancreatitis, kidney problems, and gastrointestinal disorders.

Due to potential risks, Mounjaro carries a boxed warning about thyroid C-cell tumors and is contraindicated in individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2.

Mounjaro is not suitable for individuals with type 1 diabetes and has not been established as safe for use in pediatric patients. Its use should be under the guidance of a qualified healthcare professional, with regular monitoring to manage any adverse effects and assess treatment efficacy.